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    Traumatic Brain Injury (TBI) is now recognized as a causative factor for hormonal deficiencies associated with personality changes. Psychological, physiological, and physical manifestations like; depression, anxiety, mood swings, bouts of anger, memory loss, inability to concentrate, learning disabilities, sleep deprivation, increased risk for heart attacks, strokes, high blood pressure, diabetes, loss of libido, menstrual irregularities, pre-mature menopause, obesity, loss of lean body mass, muscular weakness, and a number of other medical conditions can arise subsequent to head trauma. 

    Conventional medications (antidepressants, anti-anxiety, anti-seizure, anti-psychotic, and narcotics) do nothing to address the underlying causes that create the symptoms associated with TBI (Post-Concussion Syndrome) because they do not replenish the missing neurosteroids (brain hormones). Many individuals under conventional treatment become further dysfunctional from the over-load of medications used for treating the superficial complaints (masking). 

    Take some time and review the medical articles that are being published addressing and acknowledging the association between TBI and Hormonal Dysfunction. Dr. Mark L. Gordon was the first to provide this relationship on national television after 8 years of sharing the information that already existed. Dr. Gordon is presently lecturing to other physicians both nationally and internationally on Interventional Endocrinology and in May 2015, launched a lecture series based upon his recent book entitled:

            "TBI - A Clinical Approach to Diagnosis and Treatment"   

After 8 years of clinical trials based upon hundreds of articles we now have a Perfect Protocol:
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Neuropathophysiology of TBI
The neuro-psychobehavioral characteristics of any one individual are frequently perceived to be the result of environmental influences.  The debate over “nature and nurture” pit our genome against the influences of our environment in that, we are who we are based upon the company we keep.  Or is it the genes we express?   Neuroplasticity under the control of genes and regulated by the hormones that bathe our cerebral lobes appears to have both genomic and epigenomic influences on how we respond to a variety of environmental challenges; whether-or-not it is Nurture or Nature.  The Neuropsychopharmacology of hormones is an expanding field showing us that the regulation of reactive emotions from the limbic system is due in part to changes in the gated-ion channels of neurons and their receptors, thereby influencing our intelligence and emotional presence. It is through the modulation of receptors such as GABAA, GABAB, NMDA, Sigma-1, and AMPA that a group of hormones produced in the brain and referred to as Neurosteroids influence who and what we are perceived to be and are in the moment. The most influential Neurosteroids are those steroids that not only regulate receptors, but also the health and regeneration of neurons.  Representatives of this classification are Progesterone, Allopregnanolone, Estradiol, Testosterone, DiHydroTestosterone, Pregnenolone and their active sulfated forms all manufactured de novo in the brain.   It is the absolute or relative loss of these Neurosteroids or a sudden and precipitous change in their relative balances that can lead to alterations in how we react and how we manage our mental well-being.   This is the foundation of our evaluation and the focus of our treatment protocols.



     My position on PTSD versus TBI is very clear; if there was no physical component to your acute stressor situation that precipitated the condition referred to as Post-Traumatic Stress Disorder, then it is most likely PTSD.   On the other hand, if you had any physical component, whether it involved the head directly or indirectly, then it is a potential case of Traumatic Brain Injury.   It is my belief, based upon interpretation of 100's of articles suggesting that it is the interruption of both neurosteroids ( hormones produced in the brain that regulate who we are and how we function)  and neuroactive steroids ( produced in the peripheral glands like testes, ovaries, adrenals and so forth) that cause the change in our neuro-receptors that regulate mood and intellectual states.  It has been my 11 years of experience in treating mild and moderate TBI cases that the replenishment of neuroactive and neurosteroids to optimal levels has offered the greatest impact and resolve in each patients' condition.   MLG 07-04-2015 




Who is at risk?

Who is at risk of developing psychological  and mood disorders associated with TBI?

Any returning Veteran; PTSD that has a TBI component, Blast wave trauma, Repetitive gun fire, Motor Vehicle Accident (MVA), Motorcycle accident, Bicycle accident, Slip and fall, Football related head injuries ( NFL ), Mixed Martial Arts (MMA), Boxing, Work related head injuries (WC), Repetitive surgeries, Stroke, Cerebral hemorrhage, chemotherapeutic medication, exposure to medical/dental radiation, and just about any trauma to the body.

Those that fund our Support-A-Vet Program:

Life Extension

University Compounding Pharmacy

Dr. Ikes Pharmacy

Pure Encapsulations Supplementation

Access Medical Laboratory

Muse for a calm brain.


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